Which preposition correctly completes the sentence: He is blind _________ one eye?

Explanation

The phrase "blind in one eye" means that a person cannot see through one of their eyes. The preposition "in" is used to specify the location or condition of blindness. Using "of," "to," or "with" in this context is incorrect because they do not properly indicate the affected eye. Therefore, "in" is the correct preposition to use when describing blindness in a specific eye.