Which of the following viruses is primarily responsible for causing chronic liver disease that can progress to liver failure?

Explanation

Among the hepatitis viruses, Hepatitis C virus (HCV) is most commonly associated with chronic liver infection that can lead to progressive liver damage and ultimately hepatic failure. In contrast, Hepatitis A (HAV) and Hepatitis E (HEV) typically cause acute infections without chronic progression, while Hepatitis B (HBV) can cause chronic disease but less frequently leads to liver failure compared to HCV.